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| Product Name | Human ANG II R1-Ab (Angiotensin II Receptor 1 Antibody) ELISA Kit |
| Catalog No. | HTK-YJL-0251 |
| Synonyms | ANG II R1 Antibody ELISA Kit, Angiotensin II Receptor 1 Antibody ELISA Kit |
| Species | Human |
| UniProt ID | P30556 |
| Sample Type | Serum, plasma, cell culture supernatant, cell or tissue lysate, other liquid samples |
| Detection Method | Sandwich ELISA, Double Antigen |
| Detection Wavelength | OD450 |
| Reaction Duration | 4 hours |
| Range | 3.125-200 ng/ml |
| Sensitivity | 1.875 ng/ml |
| Storage | 2-8°C (Sealed). Don't cryopreserve. |
| Specificity | Specifically binds with ANG II R1-Ab, no obvious cross reaction with other analogues. |
| Intended Use | For research use only. |
| Product Introduction | Autoantibodies against the angiotensin II receptor type 1 (AT1R) have been implicated in various autoimmune and cardiovascular conditions, including malignant hypertension, preeclampsia, and transplant rejection. These activating antibodies can cause sustained receptor activation leading to vascular pathology. The Alta DiagnoTech human ANG-II-R1-Ab ELISA kit provides a specific method for detecting these autoantibodies in human serum, supporting research into autoimmune mechanisms in cardiovascular and obstetric diseases. |
| Product Application | • Research on preeclampsia and pregnancy-related hypertension. • Studies on autoimmune components of cardiovascular disease. • Transplant rejection and allograft vasculopathy research. • Malignant hypertension and related autoimmune disorders. |
| Product Advantages | • Autoantibody Detection: Specifically detects agonistic autoantibodies against AT1R. • Clinical Research Relevance: Supports investigation of antibody-mediated diseases. • Human Serum Validated: Optimized for clinical sample testing. • Novel Mechanism Insight: Provides tools for emerging research fields. |
For research use only, not for clinical use.
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