Rat IL-1 alpha ELISA Kit

Interleukin-1 alpha (IL-1α), a key pro-inflammatory cytokine belonging to the IL-1 family, plays a pivotal role in regulating the body’s immune response, inflammatory processes, and tissue repair mechanisms—making its accurate detection critical for advancing rat-based biomedical research.
In preclinical and basic research settings, rats are widely used as animal models due to their physiological similarity to humans, well-characterized genetic backgrounds, and suitability for studying a range of diseases (e.g., autoimmune disorders, neurodegenerative diseases, inflammatory bowel disease, and sepsis). IL-1α, as a central mediator in these pathological and physiological pathways, is often a primary target for researchers seeking to:

Elucidate the molecular mechanisms underlying inflammation and immune activation;
Evaluate the efficacy of anti-inflammatory drugs or therapeutic interventions (e.g., testing how a new compound modulates IL-1α expression in rat models of arthritis);
Monitor changes in cytokine profiles during disease progression (e.g., measuring IL-1α levels in rat serum or tissue homogenates to assess sepsis severity);
Validate the role of IL-1α in specific biological processes (e.g., wound healing, tissue regeneration, or neuroinflammation in rat brain tissue).

Traditional methods for detecting IL-1α (such as Western blotting or immunohistochemistry) often have limitations—including low throughput, high sample consumption, and the need for specialized equipment or technical expertise. Enzyme-Linked Immunosorbent Assay (ELISA) technology addresses these gaps by offering a balance of sensitivity, specificity, and ease of use, making it the gold standard for quantitative cytokine detection in most research laboratories.
The Rat IL-1 alpha ELISA Kit (Cat.No: EC-0027) from Alta Diagno Tech is specifically engineered to meet the demands of rat-focused research. It leverages highly specific antibodies and a standardized assay protocol to ensure reliable, reproducible results—enabling researchers to efficiently quantify IL-1α in a variety of rat sample types (e.g., serum, plasma, cell culture supernatants, and tissue lysates) without cross-reactivity with other rat cytokines or non-target proteins. Whether used in academic research, pharmaceutical drug discovery, or preclinical testing, this kit provides a robust tool to advance understanding of IL-1α-mediated pathways in rat models.