Human TRAIL R1 ELISA Kit is a specialized diagnostic tool designed for the quantitative measurement of human TRAIL R1 protein in various biological samples.
Alternative Names: Human TRAIL R1 is also known as DR4 (Death Receptor 4). This receptor is a member of the tumor necrosis factor receptor superfamily and plays a crucial role in apoptosis (programmed cell death).
Biological Significance: TRAIL R1 is involved in the regulation of cell death pathways, particularly in cancer cells. Its expression and activity are critical in understanding the mechanisms of apoptosis and have significant implications in cancer research and treatment.
Research Applications: This ELISA kit is widely used in research settings to study the expression levels of TRAIL R1 in different tissues and conditions. It helps researchers investigate the role of TRAIL R1 in various diseases, including cancer, autoimmune disorders, and inflammatory conditions.
Clinical Relevance: In clinical settings, the measurement of TRAIL R1 can provide valuable insights into disease progression and response to therapy. It is particularly useful in oncology for monitoring the effectiveness of treatments targeting apoptosis pathways.
High Sensitivity: The kit is designed to detect low levels of TRAIL R1 protein, ensuring accurate measurements even in samples with minimal protein concentration.
Specificity: It is specifically designed to recognize human TRAIL R1/DR4, with no cross-reactivity observed with other related proteins such as TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R2, TRAIL R3, TRAIL R4, CD178, and Granzyme B.
Convenient Format: The kit is easy to use and provides a straightforward protocol for sample preparation and analysis, making it accessible to researchers and clinicians alike.
Stability: The kit components are stable at 4°C storage conditions, ensuring long-term usability and reliability.
Versatility: Suitable for a wide range of applications, including basic research, clinical studies, and drug development.
Reliable Detection: The kit offers consistent and reliable detection of TRAIL R1, providing accurate and reproducible results.
Time-Efficient: The streamlined protocol allows for quick sample analysis, saving time and effort in the laboratory.
Cost-Effective: The kit is designed to provide high-quality results at a competitive price, making it an economical choice for both small-scale and large-scale studies.
Support: Comprehensive technical support is available to assist users with any questions or issues related to the kit's use and interpretation of results.
Customization: The kit can be customized to meet specific research needs, offering flexibility in experimental design.
In the field of apoptosis research and cancer diagnostics, there are several related products that researchers and clinicians may find useful. These include:
Human TRAIL R2 ELISA Kit: This kit is designed for the detection of TRAIL R2, another important receptor in the TRAIL signaling pathway. It complements the TRAIL R1 kit by providing a comprehensive analysis of TRAIL receptor expression.
Human TRAIL ELISA Kit: For researchers interested in measuring the ligand TRAIL itself, this kit offers a reliable method for quantifying TRAIL levels in biological samples.
Apoptosis Assay Kits: Various apoptosis assay kits are available for studying different aspects of apoptosis, such as caspase activity, DNA fragmentation, and mitochondrial changes.
Cancer Biomarker Kits: A range of ELISA kits for the detection of other cancer biomarkers, such as HER2, VEGF, and EGFR, can be used in conjunction with the TRAIL R1 kit to provide a broader understanding of cancer biology.
If you are interested in any of these related products or require customized solutions, please feel free to contact us directly.