The p53 protein, also known as tumor protein p53 or TP53, is a crucial protein that plays a vital role in preventing cancer. It is often referred to as the "guardian of the genome" due to its essential function in maintaining genomic stability.
This protein is encoded by the TP53 gene and acts as a transcription factor. It regulates the cell cycle and functions as a tumor suppressor. In response to various stress signals, such as DNA damage, hypoxia, and oncogene activation, p53 can induce cell cycle arrest, apoptosis, or senescence.
Mutations in the TP53 gene are frequently observed in a wide range of human cancers. These mutations often lead to the loss of p53's tumor-suppressive functions, highlighting its critical role in cancer development.
Research on p53 has been a focal point in the fields of cancer biology and molecular biology. Understanding its mechanisms and functions is crucial for developing new cancer therapies and diagnostic tools.
The study of p53 has also extended to other areas of biology, including aging, development, and stem cell biology. Its wide-ranging effects on cellular processes make it a key target for scientific investigation.
High Specificity: This kit is designed to recognize both natural and recombinant soluble human p53 with high specificity. It does not cross-react with other human soluble molecules, ensuring accurate detection of the target protein.
In Vitro Detection: It allows for immediate in vitro detection of human p53. This feature makes it a convenient and efficient tool for researchers and clinicians who need to assess p53 levels in biological samples.
Convenient Storage: The kit can be stored at 4°C, which is a standard laboratory condition. This makes it easy to store and maintain the kit without requiring specialized equipment.
Room Temperature Transportation: The transportation condition of room temperature ensures that the kit remains stable during shipping. This is particularly important for international orders, as it reduces the risk of damage or degradation during transit.
Reliable Detection: With its high specificity and sensitivity, this Human p53 ELISA Kit provides reliable detection of human p53 protein. This reliability is crucial for obtaining accurate results in research and clinical settings.
Time-Efficiency: The ability to perform immediate in vitro detection means that researchers can obtain results quickly. This time-efficiency is beneficial for projects with tight deadlines and for clinical applications where rapid diagnosis is important.
User-Friendly: The kit is designed to be user-friendly, making it accessible to researchers and technicians with varying levels of experience. This ease of use can help to reduce errors and improve the overall efficiency of the laboratory workflow.
Cost-Effective: By providing accurate and reliable results without the need for complex and expensive equipment, this kit offers a cost-effective solution for p53 detection. This can be particularly advantageous for laboratories with limited budgets.