Human IL-1 beta ELISA Kit

Interleukin-1 beta (IL-1β) is a crucial pro-inflammatory cytokine that plays a pivotal role in the regulation of immune responses. It is also known as catabolin or hemopoietin-1. IL-1β is synthesized as a precursor protein and is activated by caspase-1. This cytokine is involved in a variety of biological processes, including the induction of fever, the promotion of inflammation, and the regulation of hematopoiesis.
IL-1β is produced by various cell types, including monocytes, macrophages, and dendritic cells. It is also expressed in non-immune cells such as endothelial cells and fibroblasts. The production of IL-1β is tightly regulated at both the transcriptional and post-translational levels.
The discovery of IL-1β dates back to the 1970s when researchers identified a factor that could induce fever and inflammation. Since then, extensive research has been conducted to elucidate its structure, function, and mechanism of action. IL-1β has become a key target for the development of therapeutic agents for various inflammatory and autoimmune diseases.