CD44, also known as Phagocytic Glycoprotein-1 (Pgp-1) or OFA-125 antigen, is a transmembrane glycoprotein that plays a crucial role in cell adhesion, migration, and proliferation. It is widely expressed in various cell types, including hematopoietic cells, epithelial cells, and fibroblasts. CD44 is involved in numerous biological processes such as immune response, tissue repair, and cancer metastasis.
Discovery and Evolution: The discovery of CD44 dates back to the 1980s when it was first identified as a cell surface marker for hematopoietic cells. Over the years, extensive research has unveiled its complex structure and diverse functions. CD44 exists in multiple isoforms due to alternative splicing, which adds to its functional versatility.
Clinical and Research Significance: In clinical settings, CD44 has emerged as a potential biomarker for various diseases, particularly cancers. Its expression levels have been correlated with tumor progression and metastasis. In research, CD44 is a focal point for understanding cell-cell interactions, stem cell biology, and the mechanisms of tissue regeneration.
High Specificity: This Human CD44 ELISA kit is meticulously designed to recognize both natural and recombinant human soluble Pgp-1, ensuring accurate detection without cross-reactivity with other human adhesion molecules.
Immediate Detection: It enables rapid and convenient in vitro detection of human CD44, providing researchers and clinicians with timely results to support their studies and diagnoses.
User-Friendly Protocol: The kit comes with a straightforward and easy-to-follow protocol, making it accessible to users with varying levels of laboratory experience.
Stable and Convenient Storage: The kit components are stable at 4°C, eliminating the need for cumbersome cryogenic storage conditions and facilitating long-term usability.
Reliable and Consistent Results: The kit consistently delivers reliable results, thanks to its well-validated antibodies and optimized assay conditions. This reliability is crucial for obtaining reproducible data in research and clinical settings.
Time and Cost-Effective: By offering immediate detection and a user-friendly protocol, this kit saves valuable time and resources compared to more complex and time-consuming detection methods.
Versatile Applications: Its ability to detect both natural and recombinant forms of human CD44 makes it suitable for a wide range of applications, from basic research to clinical diagnostics.
Customer Support: Our team provides comprehensive technical support and assistance to ensure that users can effectively utilize the kit and achieve their research or diagnostic goals.