| Product Name | Human CD14 ELISA Kit |
| Catalog No. | EC-0055 |
| Description | Human CD14 ELISA kit is a kit for the in vitro detection of human CD14 protein using enzyme-linked adsorption reaction. |
| Species Characteristics | Human |
| Cross-reaction | No cross reactivity with other human soluble molecules. |
| Specificity | Recognizes both natural and recombinant human soluble CD14. |
| Application | It can be used for immediate in vitro detection of human CD14. |
| Storage | Store at 4°C. |
| Transportation Condition | Transportation at room temperature. |
Human CD14 is a crucial molecule in the innate immune system. It is also known as Cluster of Differentiation 14 or sCD14 (soluble CD14). This glycoprotein is primarily expressed on the surface of monocytes, macrophages, and dendritic cells.
Role in Immunity: CD14 acts as a pattern recognition receptor (PRR) that binds to lipopolysaccharides (LPS) from Gram-negative bacteria and lipoteichoic acids from Gram-positive bacteria. This binding triggers a cascade of immune responses, including the activation of signaling pathways that lead to the production of pro-inflammatory cytokines.
Clinical Significance: Elevated levels of sCD14 in the blood are associated with various inflammatory conditions, such as sepsis, cardiovascular diseases, and autoimmune disorders. It is also a biomarker for monitoring the progression of certain diseases and the effectiveness of therapeutic interventions.
Research Applications: In research, CD14 is widely studied for its role in immune cell activation, inflammation, and host-pathogen interactions. It is a key target for developing new diagnostic tools and therapeutic strategies to combat infectious and inflammatory diseases.
High Sensitivity: The Human CD14 ELISA Kit is designed to detect low levels of human CD14 protein with high accuracy.
Specificity: It recognizes both natural and recombinant human soluble CD14, ensuring reliable results.
No Cross-Reactivity: The kit does not cross-react with other human soluble molecules, providing precise measurements.
Convenient Storage: Stored at 4°C, the kit is easy to handle and maintain in laboratory conditions.
Room Temperature Transportation: The kit can be transported at room temperature, making it convenient for shipping and storage.
Reliable Detection: The kit provides consistent and reproducible results, making it a trusted tool for researchers and clinicians.
Wide Range of Applications: Suitable for both research and clinical settings, it can be used for immediate in vitro detection of human CD14.
User-Friendly: The kit is easy to use, with straightforward protocols that ensure accurate and efficient testing.
Cost-Effective: Provides high-quality results at an affordable price, making it an excellent choice for laboratories on a budget.
Support and Service: Our team offers excellent customer support and technical assistance to ensure you get the most out of our products.
For in vitro diagnostic use.
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