Human CD126, also known as Soluble Interleukin-6 Receptor (sIL-6R), is a significant protein in the field of immunology and cell biology. It is a soluble form of the IL-6 receptor that can bind to IL-6 and facilitate its signaling in cells that do not express the IL-6 receptor. This process, known as trans-signaling, plays a crucial role in various physiological and pathological processes.
Research Significance: sIL-6R is implicated in multiple diseases, including inflammatory conditions, autoimmune disorders, and certain cancers. Its detection and quantification are essential for understanding disease mechanisms and developing targeted therapies.
Discovery and Development: The discovery of sIL-6R has opened new avenues for research into cytokine signaling pathways. It has become a focal point for scientists aiming to unravel the complexities of the immune response and its dysregulation in disease states.
High Sensitivity: The Human CD126 ELISA Kit is designed to detect low levels of sIL-6R with high precision, making it suitable for a wide range of sample types.
Specificity: The kit is engineered to recognize both natural and recombinant human sIL-6R, ensuring accurate and reliable results.
Cross-Reactivity: It exhibits no cross-reactivity with other human soluble receptors, nor does it interfere with soluble gp130 or IL-6, providing highly specific detection.
Convenience: The kit is easy to use, with a straightforward protocol that minimizes the potential for user error.
Wide Application Range: This kit is ideal for both basic research and clinical studies, allowing researchers to measure sIL-6R levels in various biological samples.
Reliable Results: The high specificity and sensitivity of the kit ensure that the data obtained are accurate and reproducible.
Time-Efficient: The kit is designed to provide results quickly, saving valuable time for researchers.
Cost-Effective: By offering a reliable and efficient method for sIL-6R detection, this kit helps reduce the overall cost of research.