Human CD116, also known as Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha (GM-CSFRα), is a crucial protein involved in the regulation of immune responses and hematopoiesis. This receptor plays a vital role in the proliferation and differentiation of granulocytes and macrophages, which are essential components of the immune system.
Discovery and Research: Discovered in the late 20th century, GM-CSFRα has been extensively studied for its role in various immune-mediated diseases. It is a key target in research related to leukemia, myelodysplastic syndromes, and other hematological disorders.
Clinical Significance: Elevated levels of GM-CSFRα have been associated with certain types of cancer and inflammatory conditions. Monitoring GM-CSFRα levels can provide valuable insights into disease progression and treatment efficacy.
Scientific Applications: The Human CD116 ELISA Kit is widely used in research laboratories to measure GM-CSFRα levels in biological samples such as serum, plasma, and cell culture supernatants. This kit is an essential tool for researchers studying immune cell signaling pathways and developing therapeutic strategies.
High Sensitivity: The kit is designed to detect low levels of GM-CSFRα with high accuracy, making it suitable for a wide range of applications.
Specificity: It recognizes both natural and recombinant human soluble GM-CSFRα, ensuring reliable results.
Cross-Reactivity: The kit exhibits no cross-reactivity with other human soluble receptors, providing precise measurements.
Convenience: The kit is easy to use and requires minimal sample preparation, saving time and effort in the laboratory.
Storage and Stability: The kit is stable at 4°C, ensuring long-term usability without degradation.
Accurate Detection: Provides highly accurate and reproducible results, essential for reliable research outcomes.
Versatility: Suitable for various sample types, including serum, plasma, and cell culture supernatants, making it a versatile tool for different research needs.
Time-Efficient: The kit's straightforward protocol allows for quick and efficient sample analysis, reducing turnaround time.
Cost-Effective: Designed to be cost-effective, providing high-quality results without compromising on budget.
Support: Comprehensive technical support and documentation are available to assist users in achieving optimal results.