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Cat.No: DB-1643 Datasheet Instruction for Use
Specification Quantities
Price $1345.59–2242.65
| Product Name | Anti-Islet Cell Antibodies (ICA) ELISA Kit |
| Catalog No. | DB-1643 |
| Description | This assay employs a competitive enzyme-linked immunosorbent assay (ELISA) technique. The microplate provided with this kit is pre-coated with an antibody specific to ICA. Subsequently, standards or samples are added to the corresponding wells of the microplate along with horseradish peroxidase (HRP)-labeled ICA, followed by incubation. Under the mediation of the antibody, HRP-labeled ICA and unlabeled ICA undergo a competitive inhibition reaction. After adding the substrate solution to the wells, the degree of color development is inversely proportional to the concentration of ICA in the sample. Following termination of the color development reaction, the color intensity is measured. |
| Sample Type | Serum, plasma, other biological fluids |
| Sample Volume | 1-200 µL |
| Assay Time | 1-4.5h |
| Assay Method | ELISA |
| Detection Wavelength | 450 nm |
| Species Reactivity | Human (Homo sapiens) |
| Applications | The kit is an enzyme immunoassay for in vitro quantitative measurement of ICA in human serum, plasma, tissue homogenates and other biological fluids. ICA testing aids in the early diagnosis of type 1 diabetes, which is characterized by an autoimmune response that leads to damage to pancreatic beta cells and insufficient insulin secretion. As such, this product can be applied in various research settings, including studies using animal models of diabetes, investigations into the mechanisms of autoimmune diseases, and evaluations of the efficacy of drug interventions, thereby providing technical support for research into the molecular mechanisms underlying pancreatic beta cell dysfunction. |
| Storage and Transportation | Store at 2-8°C; shelf life: 6 months. |
For research use only, not for clinical use.
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