| Product Name | DNA Damage Detection Kit |
| Catalog No. | CQ-0088 |
| Description | DNA damage detection kit is a test kit that detects the amount of DNA damage markers by immunofluorescence staining to confirm whether DNA is damaged or not. |
| Application | This product can be used to detect DNA damage in human, mouse or rat cells or tissues by fluorescence microscopy or high content screening. |
| Storage | Store at 4°C. |
| Transportation Condition | Transportation at room temperature. |
Also Known As: DNA Damage Detection Kit, also referred to as DNA Lesion Detection Kit or DNA Oxidative Damage Kit.
DNA Damage Overview: DNA damage refers to any change in the DNA that alters its normal structure or function. This damage can be caused by a variety of factors, including exposure to ultraviolet (UV) light, ionizing radiation, chemicals, and reactive oxygen species (ROS). DNA damage is a natural occurrence and is constantly being repaired by the cell's DNA repair mechanisms.
Types of DNA Damage: There are several types of DNA damage, including base modifications, single-strand breaks, double-strand breaks, and bulky adducts. One of the most common types of DNA damage is the formation of apurinic/apyrimidinic (AP) sites, which are caused by the loss of the base component of DNA. These sites can lead to mutations if not properly repaired.
Significance in Research and Medicine: Understanding DNA damage is crucial for various fields of research and medical applications. It helps in studying the mechanisms of aging, cancer development, and the effects of environmental toxins on cellular health. Additionally, it aids in the development of therapeutic strategies for diseases associated with DNA damage.
·High Sensitivity: The kit is designed to detect low levels of DNA damage, ensuring accurate results even in samples with minimal damage.
·Colorimetric Detection: Utilizes a colorimetric method for easy and visual detection of DNA damage, which can be quantified using a microplate reader.
·Versatile Sample Types: Compatible with a wide variety of sample types, including serum, plasma, saliva, urine, and cell lysates, making it suitable for diverse research applications.
·User-Friendly Protocol: The kit includes all necessary reagents and provides a straightforward protocol, ensuring ease of use for both novice and experienced researchers.
·Time-Efficient: Delivers results in approximately 2.5 hours, allowing for rapid assessment of DNA damage.
·Cost-Effective: Provides an economical solution for the detection of DNA damage, making it an ideal choice for laboratories with varying budgets.
·Reliable Performance: Backed by rigorous testing and validation, ensuring consistent and reliable performance every time.
For in vitro diagnostic use.
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