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| Product Name | Cell Free DNA Extraction Kit (50 rxns) |
| Catalog No. | KD-HMM-0015 |
| Description | This product has a high binding capacity and low elution volume, and can be used in both automated and manual operations. |
| Features | High yield: more optimized operation process, greater access to free DNA, plasma standard sample recovery rate > 85%;
High purity: optimized buffer system, effectively removing PCR inhibitors and protein contaminants; Lower elution volume: the elution volume can be as low as 20 µL to ensure higher nucleic acid concentration; Flexible sample processing volume: free DNA can be extracted from cell-free body fluids such as 0.2-5 mL of serum or plasma. |
| Storage | Store at 2-8°C |
| Shelf Life | 2 years |
| Certification | FDA |
| Product Introduction | Cell-free DNA (cfDNA) are short, fragmented DNA molecules circulating in body fluids, released from apoptotic and necrotic cells. Its analysis, especially from blood plasma (circulating tumor DNA, ctDNA), has revolutionized non-invasive diagnostics in oncology, prenatal care, and transplant rejection monitoring. This kit is specifically optimized to capture these short, low-abundance fragments from large-volume liquid samples (e.g., 1-10 mL of plasma) while effectively removing contaminating genomic DNA from lysed blood cells. |
| Product Application | • Liquid biopsy for cancer detection, therapy monitoring, and minimal residual disease (MRD) assessment. • Non-invasive prenatal testing (NIPT) for fetal chromosomal aneuploidies. • Monitoring of organ transplant rejection (donor-derived cfDNA). • Research on cfDNA biology in other conditions like sepsis, trauma, or autoimmune diseases. |
| Product Advantages | • High Sensitivity: Designed to maximize recovery of low-concentration, short-fragment cfDNA. • Inhibitor Removal: Efficiently removes heparin, EDTA, hemoglobin, and other common plasma-borne PCR inhibitors. • Scalable Processing: Can handle variable input volumes to concentrate cfDNA from large plasma volumes. • NGS-Ready Output: Eluted cfDNA is of high purity and compatible with demanding downstream applications like library preparation for sequencing. |
For in vitro diagnostic use.
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